Which of the following is not a safety screening performed by e-prescribing?

In the realm of e-prescribing, safety screenings are crucial for ensuring that medications are prescribed in a manner that minimizes adverse effects on patients. The screenings included in e-prescribing systems typically focus on identifying potential risks such as drug interactions, allergies, and dosage errors.

Drug Interaction checks are performed to prevent potential harmful interactions between prescribed medications, ensuring that medications prescribed to a patient do not negatively affect each other. Allergy Checks involve assessing the patient's allergies to prevent prescribing medications that could trigger an allergic reaction. Dosage Verification is critical for ensuring that the medication is prescribed at a safe and effective dose based on the patient’s specific medical history, age, and other factors.

Drug-Tolerance, while important in a clinical context, specifically relates to the body’s adaptation to a drug over time and is not typically a standard safety screening associated with e-prescribing. The primary focus of e-prescribing safety screenings is to flag immediate concerns related to medication safety in the current prescribing instance rather than evaluating a patient’s tolerance to medications over time. This distinction makes Drug-Tolerance the correct answer as the item not typically included in e-prescribing safety screenings.